首页> 外国专利> MRP8/MRP14 heterodimer, or its individual components in combination, for treating and/or preventing skin diseases, wounds and/or wound-healing disturbances, having a reduced quantity of MRP8/MRP14 heterodimers

MRP8/MRP14 heterodimer, or its individual components in combination, for treating and/or preventing skin diseases, wounds and/or wound-healing disturbances, having a reduced quantity of MRP8/MRP14 heterodimers

机译:MRP8 / MRP14异二聚体或其组合的单个成分,用于治疗和/或预防皮肤疾病,伤口和/或伤口愈合障碍,减少了MRP8 / MRP14异二聚体的数量

摘要

The present invention relates to the use of an MRP8/MRP14 heterodimer, or of its individual components in combination, of at least one nucleic acid encoding the entire heterodimer or its individual components in combination, or of a cell which is expressing the entire heterodimer, or its individual components in combination, for treating and/or preventing skin diseases, wounds, and/or wound-healing disturbances having a reduced quantity of MRP8/MRP14 heterodimers, in particular diabetes-associated wounds, and to methods for identifying pharmacologically active substances which exert an influence on the function or expression of MRP8/MRP14 heterodimers.
机译:本发明涉及MRP8 / MRP14异二聚体或其组合,编码完整异二聚体的至少一种核酸或其组合的用途,或表达完整异二聚体的细胞的用途,或其组合的单独成分,用于治疗和/或预防MRP8 / MRP14异二聚体含量降低的皮肤病,伤口和/或伤口愈合障碍,尤其是与糖尿病相关的伤口,以及鉴定药理活性物质的方法它们对MRP8 / MRP14异二聚体的功能或表达产生影响。

著录项

  • 公开/公告号US2003003482A1

    专利类型

  • 公开/公告日2003-01-02

    原文格式PDF

  • 申请/专利权人 HALLE JORN-PETER;GOPPELT ANDREAS;

    申请/专利号US20020134841

  • 发明设计人 ANDREAS GOPPELT;JORN-PETER HALLE;

    申请日2002-04-29

  • 分类号C12Q1/68;G01N33/567;

  • 国家 US

  • 入库时间 2022-08-22 00:07:54

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