首页>
外国专利>
Upregulation of type III endothelial cell nitric oxide synthase by agents that disrupt actin cytoskeletal organization
Upregulation of type III endothelial cell nitric oxide synthase by agents that disrupt actin cytoskeletal organization
展开▼
机译:破坏肌动蛋白细胞骨架组织的药物上调III型内皮细胞一氧化氮合酶
展开▼
页面导航
摘要
著录项
相似文献
摘要
A use for agents that disrupt actin cytoskeletal organization is provided. In the instant invention, agents that disrupt actin cytoskeletal organization are found to upregulate endothelial cell Nitric Oxide Synthase activity. As a result, agents that disrupt actin cytoskeletal organization are useful in treating or preventing conditions that result from the abnormally low expression and/or activity of endothelial cell Nitric Oxide Synthase. Such conditions include hypoxia-induced conditions. Subjects thought to benefit mostly from such treatments include nonhyperlipidemics and nonhypercholesterolemics, but not necessarily exclude hyperlipidemics and hypercholesterolemics.
展开▼