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Use of monoclonal antibodies and functional assays for prediction of risk of opportunistic infection
Use of monoclonal antibodies and functional assays for prediction of risk of opportunistic infection
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机译:单克隆抗体和功能分析在预测机会性感染风险中的应用
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摘要
The present invention is drawn to methods of detecting and monitoring a subject at risk for opportunistic infection. More particularly, the methods comprise monitoring key monocyte functions and surrogate cell surface markers on monocytes to predict subjects at risk for opportunistic infection. Specific monocyte key functions comprise measurements of phagocytic activity and transendothelial migration. Another aspect of the present invention is a kit comprising the compositions of the present invention used to detect or monitor a subject at risk for opportunistic infection.
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