;from a compound having the formula: chemistry chemdraw filechemistry mol file;wherein R1 is hydrogen, fluorine, chlorine or SiR5R6R7, wherein R5, R6, and R7 are independently the same or different an alkyl group or an aryl group, R2 is an alkyl group, R3 is a protecting group, R4 is an alkyl group, an allyl group, a propargyl group —CO2H, or a benzyl group, R8 is —CO2R10, wherein R10 is an alkyl group or an aryl group, X1 is OH and X2 is H, includes the step of exposing compound (III) to at least one of an organic acid or an inorganic acid. A compound has the general formula (III)."/>
Intermediates and methods of preparation of intermediates in the enantiomeric synthesis of (20R)homocamptothecins and the enantiomeric synthesis of (20R)homocamptothecins
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Intermediates and methods of preparation of intermediates in the enantiomeric synthesis of (20R)homocamptothecins and the enantiomeric synthesis of (20R)homocamptothecins
Intermediates and methods of preparation of intermediates in the enantiomeric synthesis of (20R)homocamptothecins and the enantiomeric synthesis of (20R)homocamptothecins
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机译：（20R）喜树碱对映体合成和（20R）喜树碱对映体合成的中间体和制备方法
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摘要
A method of synthesizing a compound having the formula: chemistry chemdraw filechemistry mol file;from a compound having the formula: chemistry chemdraw filechemistry mol file;wherein R1 is hydrogen, fluorine, chlorine or SiR5R6R7, wherein R5, R6, and R7 are independently the same or different an alkyl group or an aryl group, R2 is an alkyl group, R3 is a protecting group, R4 is an alkyl group, an allyl group, a propargyl group —CO2H, or a benzyl group, R8 is —CO2R10, wherein R10 is an alkyl group or an aryl group, X1 is OH and X2 is H, includes the step of exposing compound (III) to at least one of an organic acid or an inorganic acid. A compound has the general formula (III).
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机译：一种具有下式的化合物的合成方法： <图像文件=“ US20030073840A1-20030417-C00001.GIF” he =“ 85.92885” id =“ EMI-C00001” imgContent =“ undefined” imgFormat =“ GIF” wi =“ 144.9819“ /> 化学chemdraw文件 化学分子文件 ;来自具有以下化学式的化合物： <图像文件=“ US20030073840A1-20030417-C00002.GIF” he =“ 85.70205” id =“ EMI-C00002” imgContent =“ undefined” imgFormat =“ GIF” wi =“ 152.4096“ /> 化学化学绘图文件 化学摩尔文件 ;其中R 1 是氢，氟，氯或SiR 5 R 6 R 7 ，其中R 5 ，R 6 和R 7 独立地为相同或不同的烷基或芳基，R 2 是烷基，R 3 是保护基，R 4 是烷基，烯丙基，炔丙基＆mdash; CO 2 H或苄基，R 8 是＆mdash; CO 2 R 10 10 是烷基或芳基，X 1 是OH，X 2 是H的Sup>包括以下步骤： Ë使化合物（III）与有机酸或无机酸中的至少一种接触。化合物具有通式（III）。
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