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like rare earth complex, how to use to reduce the interference in fluorescence analysis using method of reducing interference and that in the fluorescence analysis using the same
like rare earth complex, how to use to reduce the interference in fluorescence analysis using method of reducing interference and that in the fluorescence analysis using the same
Rare earth macrocyclic complexes, characterised in that they consist of at least one rare earth salt forming a complex with a macrocyclic compound of formula (I), in which bivalent radicals A , B , C and D which may be the same or different, are hydrocarbonated chains optionally containing one or more heteroatoms, at least one of said radicals including at least one molecular pattern or essentially consisting of a molecular pattern with a triplet energy exceeding that of the emissive level of the complex rare earth ion, at least one of said radicals consisting of a substituted or unsubstituted nitrogenous heterocyclic system, at least one of the nitrogen atoms of which carries an oxy group, and one of the C or D radicals possibly being nonexistant; X1 and X2, which may be the same or different, are hydrogen or a hydrocarbonated chain (CH2)n optionally interrupted by 1 or more heteroatoms, wherein n is an integer from 1 to 10, with the proviso that when the radicals A and/or B are a nitrogenous heterocyclic system, at least one of the nitrogen atoms of which carries an oxy group, the radicals C and/or D be chosen from the biquinolines, the bi-isoquinolines, the bipyridines, the ter-pyridines, the coumarines, the bipyrazines, the bipyrimidines and the pyridines. The complexes are useful in the reduction of disturbances in an assay using fluorescence.
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机译：稀土大环配合物，其特征在于它们由至少一种与式（I）的大环化合物形成配合物的稀土盐组成，其中二价基团A，B，C和D可以相同或不同。任选地包含一个或多个杂原子的烃基链，所述基团中的至少一个包括至少一个分子模式或基本上由具有三重态能量超过复合稀土离子发射能级的三重态能量的分子模式组成，所述至少一个由取代或未取代的含氮杂环系统组成的基团，其至少一个氮原子带有一个氧基，并且C或D基团之一可能不存在; X 1和X 2可以相同或不同，是氢或可被1个或多个杂原子中断的烃链（CH2）n，其中n为1至10的整数，条件是当基团A和//或B为含氮杂环系统，其氮原子中的至少一个带有氧基，基团C和/或D选自联喹啉，联二异喹啉，联吡啶，三联吡啶，香豆素，联吡嗪，联嘧啶和吡啶。该复合物可用于减少使用荧光的测定中的干扰。
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