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Diagnostic kit for prenatal detection of trisomy 21, comprises primer pairs specific for amplification of short tandem repeat regions in chromosome 21
Diagnostic kit for prenatal detection of trisomy 21, comprises primer pairs specific for amplification of short tandem repeat regions in chromosome 21
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机译：用于21三体性的产前检测的诊断试剂盒，包括特异性扩增21号染色体上短串联重复序列区域的引物对
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摘要
Diagnostic kit for detecting trisomy 21 in a human fetus comprises at least two pairs of oligonucleotide primers suitable for amplification, by polymerase chain reaction (PCR), of both strands of a target DNA sequence, i.e. a short tandem repeat region (X) of human chromosome 21. Independent claims are also included for the following: (1) microarray for detecting trisomy 21, especially a DNA chip, comprising an array of many separate fields, at least one of which carries an oligonucleotide able to hybridize to DNA that is part of X; and (2) method for detecting trisomy 21.
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