首页>
外国专利>
Identifying agents for treating cardiovascular disease, comprises determining the ability of potential agents to modify interaction between beta3 endonexin and beta3 integrin
Identifying agents for treating cardiovascular disease, comprises determining the ability of potential agents to modify interaction between beta3 endonexin and beta3 integrin
展开▼
机译：鉴定治疗心血管疾病的药物包括确定潜在药物改变β3内毒素和β3整联蛋白之间相互作用的能力
展开▼
页面导航
摘要
著录项
相似文献
摘要
Identifying agents (I) for treatment of arteriosclerosis (or resulting unstable plaques), acute coronary thrombosis, cardiac infarction, stroke, peripheral arterial occlusive diseases, chronic venous ulcers and restenosis, comprises using beta 3 endonexin (A), long or short. Independent claims are also included for the following: (1) identifying compounds (B) that inhibit binding of short (A), or the effect of long (A), on beta 3-integrin (II); (2) identifying compounds that modify competition between long and short (A) for binding to (II); (3) test mixture for (a); (4) kit of parts for identifying (B); (5) (B) identified by the method of (1); and (6) a pharmaceutical composition containing a compound (D) that modifies (II)-dependent intracellular processes.
展开▼
