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METHOD FOR PREDICTING THE DEVELOPMENT OF POLYORGANIC DEFICIENCY IN THE THIRD TRIMESTER OF PREGNANCY

机译:预测妊娠第三学期中多器官缺乏症发展的方法

摘要

FIELD: medicine, obstetrics. SUBSTANCE: the system of acute-phase proteins is tested in pregnant women at the third trimester of pregnancy by detecting the level of fibronectin, studying the system of hemostasis, calculating the level of blood D-dimers and the number of "active" fetal erythrocytes in peripheral blood, the value of hemodynamics system - structural point AD and diagnostic index F is calculated by the formula: F = K1 0.0018 - K2 0.2021865 + K3 0.42014 - K4 0.00301 + K5 0.01114 + 0.04018, where K1 - structural point AD (conventional unit); K2 - the level of D-dimers (ng/ml); K3 - the number of active blood platelets (109/l); K4 - the number of fetal erythrocytes in peripheral blood (%); K5 - the level of fibronectin (g/l). If F is below 0.05 one should conclude on no risk of polyorganic deficiency development, if F is above 0.05 the development of polyorganic deficiency is predicted, moreover, if F corresponds to 0.07-0.11 the damage of two vital systems is predicted: cardiovascular and hepatolienal ones, if F is equal to 0.1-2 the damage of three vital systems is predicted: cardiovascular, hepatolienal and hemostasis and a maximum risk for development of thrombohemorrhagic complications, in case F corresponds to 0.2-0.4 the development of irreversible states with lethal results is predicted. The method favors to reveal in due time the risk group for development of the given syndrome and monitor patient's state during gestation. EFFECT: higher efficiency of prediction. _
机译:领域:医学,妇产科。物质:通过检测纤连蛋白的水平,研究止血系统,计算血液D-二聚体的水平和“活性”胎儿红细胞的数量,对孕妇在妊娠晚期进行了急性期蛋白系统的测试在外周血中,血液动力学系统-结构点AD和诊断指数F的值可通过以下公式计算:F = K1 0.0018-K2 0.2021865 + K3 0.42014-K4 0.00301 + K5 0.01114 + 0.04018,其中K1-结构点AD(常规单元); K2-D-二聚体水平(ng / ml); K3-活动性血小板数(10 9 / l); K4-外周血中胎儿红细胞的数量(%); K5-纤连蛋白水平(g / l)。如果F低于0.05,则应该推断没有多器官缺乏症的风险,如果F高于0.05,则可以预测出多器官缺乏症的发生,此外,如果F对应于0.07-0.11,则可以预测两个重要系统的损害:心血管和肝烯醛如果F等于0.1-2,则可以预测三个生命系统的损害:心血管,肝肾和止血以及血栓性出血性并发症发展的最大风险,如果F等于0.2-0.4,则不可逆状态的发展具有致命的结果被预测。该方法有利于在适当的时候揭示给定综合征发展的风险类别,并在妊娠期间监测患者的状态。效果:更高的预测效率。 _

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