首页> 外国专利> A SECOND HUMAN HEPARANASE, AND SPLICE VARIANTS THEREOF, WITH A PREDOMINANT EXPRESSION IN SKELETAL MUSCLE, HEART AND PANCREAS

A SECOND HUMAN HEPARANASE, AND SPLICE VARIANTS THEREOF, WITH A PREDOMINANT EXPRESSION IN SKELETAL MUSCLE, HEART AND PANCREAS

机译:第二种人类肝转移酶及其片段变种,在骨骼肌,心脏和胰腺中主要表达

摘要

The present invention relates to the field of carbohydrates and more specifically to the field of heparan sulphate proteoglycans. A polynucleotide has been identified encoding heparanase activity. This is the second gene encoding heparanase catalytic activity which is identified in humans. Several splice variants of said gene have been identified with a specific expression pattern in skeletal muscle, heart and pancreas.
机译:本发明涉及碳水化合物领域,更具体地涉及硫酸乙酰肝素蛋白聚糖领域。已经鉴定出编码乙酰肝素酶活性的多核苷酸。这是在人类中鉴定的编码乙酰肝素酶催化活性的第二个基因。已经鉴定出所述基因的几种剪接变体在骨骼肌,心脏和胰腺中具有特定的表达模式。

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