首页> 外国专利> PULMONARY DELIVERY OF RIBAVIRIN OR LEVOVIRINamp;trade; FOR SYSTEMIC AND QUASI-SYSTEMIC TREATMENT OF DISEASE

PULMONARY DELIVERY OF RIBAVIRIN OR LEVOVIRINamp;trade; FOR SYSTEMIC AND QUASI-SYSTEMIC TREATMENT OF DISEASE

机译:利巴韦林或左叶病毒素的贸易和贸易;用于疾病的系统和拟系统治疗

摘要

A method of treating a systemic viral disease in a patient has a first step in which the disease is correlated with an increase in Type 1 cytokine activity and a decrease in Type 2 activity. In a further step, a systemic dosage of a drug is identified that is effective to increase the Type 1 activity and decrease the type 2 activity, wherein the drug is Ribavirin or Levovirin™ and in a still further step, the dosage of the drug is administered to the patient via pulmonary delivery. A further method of treating a viral disease has a first step in which the disease is correlated with an infection of dendritic cells, and the dendritic cells are targeted by administering Ribavirin or Levovirin™ via a pulmonary aerosol.
机译:治疗患者的全身性病毒性疾病的方法具有第一步,其中该疾病与1型细胞因子活性的增加和2型活性的降低相关。在进一步的步骤中,鉴定了可有效增加1型活性和降低2型活性的药物的全身剂量,其中所述药物为利巴韦林或左旋韦林™并且在进一步的步骤中,通过肺部递送将药物剂量给予患者。另一种治疗病毒性疾病的方法具有第一步,其中该疾病与树突状细胞的感染有关,并且通过施用利巴韦林或左旋韦林&trade来靶向树突状细胞。通过肺气雾剂。

著录项

  • 公开/公告号WO0145642A3

    专利类型

  • 公开/公告日2001-12-13

    原文格式PDF

  • 申请/专利权人 ICN PHARMACEUTICALS INC.;ZEYTINOGLU FUESUN;

    申请/专利号WO2000US42821

  • 发明设计人 ZEYTINOGLU FUESUN;

    申请日2000-12-13

  • 分类号A61K31/70;A61K31/41;

  • 国家 WO

  • 入库时间 2022-08-22 00:38:33

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