首页> 外国专利> USE OF SELECTIN-BINDING PREGNANCY PROTEINS, LIPOSOMES, NATIVE MUCIN FRAGMENTS AND MIMETIC COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF INFLAMMATORY DISEASES, FOR PREVENTING METASTATIC SPREAD AND FOR THE PROPHYLAXIS OF TUMOUR DISEASES

USE OF SELECTIN-BINDING PREGNANCY PROTEINS, LIPOSOMES, NATIVE MUCIN FRAGMENTS AND MIMETIC COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF INFLAMMATORY DISEASES, FOR PREVENTING METASTATIC SPREAD AND FOR THE PROPHYLAXIS OF TUMOUR DISEASES

机译:结合选择蛋白的妊娠蛋白,脂质体,天然粘蛋白片段和假性化合物用于治疗和预防炎症性疾病,预防转移性传播和预防肿瘤性疾病

摘要

The invention relates to the use of selectin-binding active ingredients, inthe form of pregnancy proteins or fragments thereof, liposomes containingcalcium-binding compounds, mucin fragments originating from native sources orderived from the same, or mimetic compounds imitating sialylated Lewiscarbohydrate structures, or combinations thereof, for the treatment andprophylaxis of diseases in the development of which inflammatory processesplay a role, for example, auto-immune diseases, transplantations, andarteriosclerosis. Inflammatory diseases in terms of the invention can be of aninfectious or non-infectious nature. The invention also relates to the use ofsaid active ingredients for partially or fully preventing the metastaticspread of tumours. The administration of the active ingredients can be carriedout in a prophylactic manner or in conjunction with, for example, an ablationof the primary tumour or a biopsy. The invention further relates to the use ofsaid active ingredients for the prophylaxis of tumour diseases.
机译:本发明涉及选择素结合活性成分在药物治疗中的用途。怀孕蛋白质或其片段的形式,脂质体含有钙结合化合物,源自天然来源的粘蛋白片段或衍生自相同或模仿唾液酸化路易斯的模拟化合物碳水化合物结构或其组合,用于治疗和预防炎症过程的发展发挥作用,例如自身免疫性疾病,移植和动脉硬化。根据本发明的炎性疾病可以是传染性或非传染性。本发明还涉及使用所述活性成分,用于部分或完全防止转移肿瘤扩散。可以进行活性成分的给药以预防性方式或与消融结合使用原发肿瘤或活检标本。本发明还涉及以下方面的用途:所说的预防肿瘤疾病的有效成分。

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