首页> 外国专利> Bioprocess for the high-yield production of food flavor-acceptable jasmonic acid and methyl jasmonate, novel jasmonic acid isomer produced thereby and uses thereof

Bioprocess for the high-yield production of food flavor-acceptable jasmonic acid and methyl jasmonate, novel jasmonic acid isomer produced thereby and uses thereof

机译:用于高产食品风味可接受的茉莉酸和茉莉酸甲酯的生物方法,由此产生的新型茉莉酸异构体及其用途

摘要

Described is a bioprocess for the high-yield production of food flavor-acceptable jasmonic acid and methyl jasmonate, as well as a novel jasmonic acid isomer produced thereby and organoleptic uses thereof. The process yields at least 5% of the “cis” isomer defined according the structure: embedded image;(wherein R is hydrogen or methyl) or at least 5% of the “cis” isomer defined according to the structure: embedded image;(wherein R is hydrogen or methyl). Compositions containing at least 98% of the isomer having the structure: embedded image;with an optical rotation (&agr;D20) of +58° are novel. Compositions containing at least 98% of the isomer having the structure: embedded image;with an optical rotation (&agr;D20) of +58° are also novel. The process of our invention comprises the cultivation under aerobic condition of one or more specific strain of Diplodia gossypina in a nutrient medium followed either by (1) isolation of the jasmonic acid product or (2) esterification of the jasmonic acid to form methyl jasmonate followed by the isolation of the methyl jasmonate and novel products produced by such process.
机译:描述了一种高产量生产食品风味可接受的茉莉酸和茉莉酸甲酯的生物方法,以及由此生产的新型茉莉酸异构体及其感官用途。该方法产生的“顺式”含量至少为5%。根据结构定义的异构体:<化学id =“ CHEM-US-00001”> <图像alt =“嵌入式图像” file =“ US06458569-20021001-C00001.GIF” he =“ 66.7359” id =“ EMI-C00001” imgContent =“ undefined” imgFormat =“ GIF” wi =“ 84.73815” /> ;(其中R为氢或甲基)或至少5%的“顺式”根据结构定义的异构体:<化学id =“ CHEM-US-00002”> <图像alt =“嵌入式图像” file =“ US06458569-20021001-C00002.GIF” he =“ 60.98085” id =“ EMI-C00002” imgContent =“未定义” imgFormat =“ GIF” wi =“ 98.658” /> ;(其中R为氢或甲基)。包含至少98%的异构体的组合物具有以下结构: “嵌入式图像” ;并带有旋光度(&agr; D 20 )的&plus; 58&deg;是新颖的。包含至少98%的异构体的组合物具有以下结构: “嵌入式图像” ;并带有旋光度(&agr; D 20 )的&plus; 58&deg;也是新颖的。本发明的方法包括在有氧条件下在营养培养基中培养一或多种特异双孢霉的特异菌株,然后(1)分离茉莉酸产物或(2)酯化茉莉酸产物。茉莉酸形成茉莉酸甲酯,然后分离茉莉酸甲酯和由该方法生产的新产物。

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