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Method for detecting procoagulant genetic and metabolic conditions associated with, and potentially predispositional for, activation of the coagulation response

机译:用于检测与凝血反应的激活有关并可能易于诱发凝血的促凝血遗传和代谢状况的方法

摘要

Methods for diagnosing and identifying genetic and metabolic factors associated with a physiologic procoagulant predisposition for and concurrent activation of the coagulation response in patients suffering from conditions such as chronic fatigue syndrome, fibromyalgia, Gulf War illness and cardiovascular disease are disclosed. Diagnostic assays utilized in the methods include measurement of blood levels of Protein C, Protein S, antithrombin, activated protein C resistance, prothrombin plasminogen activator inhibitor-1, lipoprotein (a) and homocysteine. Treatment regimens include anticoagulant therapies comprising administering warfarin or heparin as needed.
机译:公开了用于诊断和鉴定与患有诸如慢性疲劳综合症,纤维肌痛,海湾战争疾病和心血管疾病的病症的患者的凝血反应的生理易感性和同时激活凝血反应相关的遗传和代谢因子的方法。该方法中使用的诊断测定包括测量蛋白C,蛋白S,抗凝血酶,活化蛋白C抵抗力,凝血酶原纤溶酶原激活物抑制剂1,脂蛋白(a)和同型半胱氨酸的血药浓度。治疗方案包括抗凝疗法,包括根据需要给予华法林或肝素。

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