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Gastroretentive controlled release microspheres (Microspheres) for improved drug delivery

机译:胃滞留控释微球(Microspheres)用于改善药物输送

摘要

There is provided a drug delivery composition for the controlled release of an active agent in the stomach environment over a prolonged period of time, which comprises a microsphere comprising an active ingredient in the inner core of the microsphere and (i) a rate controlling layer of a water insoluble polymer and (ii) an outer layer of a bioadhesive agent in the form of a cationic polymer.
机译:提供了用于在胃环境中长时间控制释放活性剂的药物递送组合物,其包含在微球的内芯中包含活性成分的微球和(i)速溶层的速率控制层。水不溶性聚合物和(ii)阳离子聚合物形式的生物粘合剂的外层。

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