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High-throughput assay for screening and its combinatorial compound libraries for directed

机译:高通量筛选方法及其组合化合物库用于定向

摘要

including a collection of predetermined nucleoside peptide molecule for suppressing the carbohydrate processing enzyme to transfer sugar to a receptor which is selected from a sugar nucleotide donors (57) is [Abstract] selected, combinatorial libraries have been disclosed. Here, nucleoside peptide molecules, cap monomer that is associated with (c) spacer monomers and spacer monomers, conjugated with the peptide mimetic or nucleoside monomers containing (a) nucleoside monomers, (b) amide chain amino acid residue 1 or more I contain. The nucleoside peptide molecule, and is characterized in that the identity of the one element are different from each other, at least one nucleoside monomer, or monomer cap spacer monomers.
机译:[摘要]选择了包括用于抑制碳水化合物加工酶以将糖转移至选自糖核苷酸供体的​​受体的预定核苷肽分子的集合[57],公开了组合文库。在此,核苷肽分子,与(c)间隔基单体和间隔基单体缔合的帽状单体,与包含(a)核苷单体,(b)1个以上的酰胺链氨基酸残基的肽模拟物或核苷单体共轭而成。核苷肽分子,其特征在于一种元素,至少一种核苷单体或单体帽间隔基单体的身份彼此不同。

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