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Methods and assay kits for detecting altered mononuclear cell phenotype related to a pro-tumor immune response
Methods and assay kits for detecting altered mononuclear cell phenotype related to a pro-tumor immune response
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机译:用于检测与促肿瘤免疫反应有关的改变的单核细胞表型的方法和检测试剂盒
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摘要
A method for screening for a pro-tumor immune response according to the present invention, the method comprises: contacting a clinical sample with one or more detector molecules for detecting, and then determining the amount of, mononuclear cell phenotype in the sample; and (b) comparing the amount of mononuclear cell phenotype determined in the sample to a reference value for the mononuclear cell phenotype; wherein a significant difference in the amount of mononuclear cell phenotype determined as compared to the reference value may be an indicator of the presence of a pro-tumor immune response. Also provided are assay kits for determining an amount of mononuclear cell phenotype in performing the methods according to the present invention.
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