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Recombinant polypeptide based on the primary sequence of the invariant chain with at least one primary sequence of a specific T-cell epitope or a protein derivative and nucleic acids coding for this recombinant polypeptide
Recombinant polypeptide based on the primary sequence of the invariant chain with at least one primary sequence of a specific T-cell epitope or a protein derivative and nucleic acids coding for this recombinant polypeptide
The present invention is relative to nucleic acids containing at least one nucleic acid sequence coding for a recombinant polypeptide, which recombinant polypeptide contains at least partially the primary sequence of the invariant chain and at least one primary sequence from a specific T-cell epitope and is processed in a desired manner in antigen-presenting cells for binding the specific T-cell epitope to MHC II molecules.
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