首页> 外国专利> STRAIN OF AVIAN INFLUENZA A VIRUS (H5N2) GKV N 2340 FOR INFLUENZA INFECTION MODELLING

STRAIN OF AVIAN INFLUENZA A VIRUS (H5N2) GKV N 2340 FOR INFLUENZA INFECTION MODELLING

机译:禽流感病毒感染的禽流感病毒(H5N2)GKV N 2340菌株

摘要

FIELD: virology. SUBSTANCE: invention relates to the strain of avian influenza A virus. Proposed strain, in contrast to other strains with subtype of hemagglutinine H5, shows no pathogenicity for birds and humans. Adapted strain is obtained by passages of the parent virus A/mallard duck/Pennsylvania/10218/84 (H5N2) through white mice lungs. Obtained strain is designated for research of genetic bases of interspecies barrier overcoming, detection of phylogenetic and ecological association of viruses isolated for different times in different geographic regions. Claimed influenza virus damages mouse lung that are identified as viral bronchopneumonia that resembles by many traits with human viral bronchopneumonia. Strain of avian influenza A virus (H5N2) is stored in collection of laboratory of museum strains of Institute of virology RAMS-GKV at N 2340. EFFECT: strain of influenza virus A indicated above, valuable properties. 3 tbl, 1 ex
机译:领域:病毒学。物质:本发明涉及禽流感A病毒株。与其他具有血凝素H5亚型的菌株相比,拟议的菌株对鸟类和人类没有致病性。通过使亲本病毒A /野鸭/宾夕法尼亚州/ 10218/84(H5N2)通过白色小鼠肺部获得适应的菌株。获得的菌株被指定用于研究种间障碍克服的遗传基础,检测在不同地理区域不同时间分离的病毒的系统发生和生态联系。声称的流感病毒会损害小鼠肺脏,这种肺脏被确定为病毒性支气管肺炎,与人病毒性支气管肺炎的许多特征相似。禽流感A病毒(H5N2)菌株存储在病毒学RAMS-GKV研究所博物馆菌株的实验室中,编号N2340。效果:上述流感病毒A株,有价值的特性。 3汤匙,1前

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