PURPOSE: An antagonist to platelet activating factor(PAF) is provided which is excellent in PAF antagonism, hopeful of displaying excellent effects for improving/preventing various diseases and allergic disorders caused by the PAF antagonism. CONSTITUTION: The platelet activating factor antagonist contains (20s)-ginsenoside Rg3 and/or ginsenoside Rg5 as an effective component. The antagonist can be used for various diseases such as asthma, allergy, arthritis, rheumatism, acute inflammation, anaphylaxis, retinitis, hepatitis, pancreatitis, nephritis, nasal inflammation, atopic dermatitis, cardiac anaphylaxis, endotoxic shock, central nervous system damage or the like. This antagonist also can be used as an auxiliary agent for treatment of inflammation.
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