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Composition for promoting hematopoietic stem cell and platelet progenitor cell proliferation containing antler extract
Composition for promoting hematopoietic stem cell and platelet progenitor cell proliferation containing antler extract
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机译:包含鹿茸提取物的促进造血干细胞和血小板祖细胞增殖的组合物
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摘要
The present invention provides a composition for promoting hematopoietic stem and platelet progenitor cell (megakaryocyte) proliferation, and a chloroform extract of such antler, containing a specific extract of antler, particularly chloroform extract of antler, and fractions separated and purified therefrom. A method for extracting, separating and purifying fractions. In addition, the present invention confirms that the compounds represented by the following formula (1) as the active ingredient showing the hematopoietic stem cell and platelet progenitor proliferation promoting activity in the extract of the antler, the synthesis method thereof and hematopoietic containing them as an active ingredient Provided are compositions for promoting proliferating parental and platelet progenitor cells, and also novel compounds in compounds of formula (I).;[Formula 1];Wherein R 1 / R 2 is 9-octadecenoyl / hexadecanoyl, hexadecanoyl / 9-octadecenoyl, hexadecanoyl / 9,12-octadecadienoyl, hexadecanoyl / 9, 12,15-octadecaterienoyl or hexadecanoyl / 5,8,11,14-eicotetraenoyl, and R 3 represents acetyl.
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