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Novel Form Of Irbesartan Methods For Obtaining Said Form And Pharmaceutical Compositions Containing Same

机译:厄贝沙坦的新颖形式,用于获得所述形式和包含该形式的药物组合物

摘要

The present invention relates to irbesartan form A having a crystalline habit modified to a length / width ratio of from 1: 1 to 10: 1, preferably from 1: 1 to 5: 1, /RTI The method comprises applying at least a temperature oscillating step to a crystalline suspension of irbesartan form A having a needle comb or applying a mechanical oscillating step to a crystalline suspension of irbesartan form A having an irregular comb, It is characterized by applying shear. The present invention also relates to a pharmaceutical composition containing the irbesartan crystalline comb.
机译:本发明涉及具有结晶习性的厄贝沙坦A型,其晶体的长/宽比为1:1至10:1,优选为1:1至5:1。对具有针梳的厄贝沙坦A型结晶悬浮液进行温度振荡步骤,或对具有不规则梳子的厄贝沙坦A型结晶悬浮液进行机械振荡步骤,其特征在于施加剪切力。本发明还涉及含有厄贝沙坦结晶梳的药物组合物。

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