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Porcine endogenous retrovirus (poerv) expressed in guinea pig and corresponding animal models

机译:在豚鼠和相应动物模型中表达的猪内源性逆转录病毒(poerv)

摘要

The present invention relates to the infection of iCavia porcellus/i (guinea pig) with porcine endogenous retrovirus (PoERV) and uses of infected guinea pig as an animal model for amongst other things examining the kinetics and tissue profile of infection of PoERV, production of an attenuated PoERV vaccine, testing vaccines, as well as determining PoERV functioning and expression in response to immunosuppressive drugs.
机译:本发明涉及猪内源性逆转录病毒(PoERV)对豚鼠(Cavia porcellus)(豚鼠)的感染,以及被感染的豚鼠作为动物模型的用途,其中所述动物模型用于检查感染的动力学和组织特征。 PoERV的生产,PoERV减毒疫苗的生产,测试疫苗以及确定PoERV对免疫抑制药物的反应和表达。

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