首页> 外国专利> VACCINE COMPOSITION COMPRISING HUMAN PAPILLOMA VIRUS 16 L1 VIRUS-LIKE PARTICLE (HPV 16 L1 VLP), HUMAN PAPILLOMA VIRUS 18 L1 VIRUS-LIKE PARTICLE (HPV 18 L1 VLP) AND 3-DE-O-ACYLATEDMONPHOSPHORYL LIPID A (3D-MPL) AND ALUM

VACCINE COMPOSITION COMPRISING HUMAN PAPILLOMA VIRUS 16 L1 VIRUS-LIKE PARTICLE (HPV 16 L1 VLP), HUMAN PAPILLOMA VIRUS 18 L1 VIRUS-LIKE PARTICLE (HPV 18 L1 VLP) AND 3-DE-O-ACYLATEDMONPHOSPHORYL LIPID A (3D-MPL) AND ALUM

机译：包含人乳头瘤病毒16升L1病毒颗粒（HPV 16 L1 VLP），人乳头瘤病毒18升L1病毒颗粒（HPV 18 L1 VLP）和3-DE-O-酰化酰基磷脂A（3D-MPL）的疫苗组合物明矾

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摘要

Novel combined vaccine compositions are provided, comprising a herpes simplex virus (H9V) antigen and a HPV antigen and optionally in addition one or more of the following: an EBV antigen, a hepatitis A antigen or inactivated attenuated virus, a hepatitis B viral antigen, a VZV antigen, a HCMV antigen, a Toxoplasma gondii antigen. The vaccine compositions are formulated with an adjuvant which is a preferential stimulator of TH1 cell response such as 3D-MPL and Q921.

机译：提供了新颖的组合疫苗组合物，其包含单纯疱疹病毒（H9V）抗原和HPV抗原，并可选地还包含以下一种或多种：EBV抗原，甲型肝炎抗原或灭活的减毒病毒，乙型肝炎病毒抗原， VZV抗原，HCMV抗原，弓形体抗原。该疫苗组合物与佐剂一起配制，该佐剂是TH1细胞应答的优先刺激剂，例如3D-MPL和Q921。

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公开/公告号CA2443214A1

专利类型
公开/公告日2001-03-15

原文格式PDF
申请/专利权人 SMITHKLINE BEECHAM BIOLOGICALS S.A.;
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申请/专利号CA20002443214
发明设计人 WETTENDORFF MARTINE ANNE CECILE;
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申请日2000-09-07
分类号A61K39/39;A61K47/02;A61K39/12;A61P31/12;
国家 CA
入库时间 2022-08-22 01:21:17

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