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Pharmaceutical composition comprising hyaluronan (Mr less than 750,00) and a disease modifier (cytokine, a peptide mimicking a cytokine or a protein mimicking a cytokine) to enhance delivery of disease modifiers
Pharmaceutical composition comprising hyaluronan (Mr less than 750,00) and a disease modifier (cytokine, a peptide mimicking a cytokine or a protein mimicking a cytokine) to enhance delivery of disease modifiers
A pharmaceutical composition component comprising hyaluronan binding motif (HBM) peptide of the formula B(X7)B, in which B is either arginine (R) or lysine (K) and X7 contains no acidic residues and at least one basic amino acid interposed between a form of hyaluronan having a molecular weight (protein standard) less than 750,000 daltons and a disease modifier which comprises a peptide or protein. The HBM protects the therapeutic peptide or protein from protease attack or immune system recognition.
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