首页> 外国专利> Benzothiophene, benzofuran and indolethiazepinons, oxazepinons and diazepinons, pharmaceutical composition, method of inhibiting the leucocytes adherence to the endothelial cells for inflammatory diseases treatment and method of treatment of the mammals affected by the HIV infection

Benzothiophene, benzofuran and indolethiazepinons, oxazepinons and diazepinons, pharmaceutical composition, method of inhibiting the leucocytes adherence to the endothelial cells for inflammatory diseases treatment and method of treatment of the mammals affected by the HIV infection

机译：苯并噻吩，苯并呋喃和吲哚并噻嗪酮，恶嗪酮和二氮杂pin烯，药物组合物，抑制白细胞粘附于内皮细胞以治疗炎症性疾病的方法以及治疗受HIV感染的哺乳动物的方法

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摘要

The invention refers to chemistry and medicine, namely, to the compounds of formula (I): CHFORMor to the acid additive salts used for treatment of inflammatory diseases and HIV infection.Summary of the invention consists in synthesis of the benzothiophene, benzofuran and indolethiazepinones, oxazepinones and diazepinones of the formula (1), utilized as active ingredients in the pharmaceutical composition inhibiting leucocyte adherence to the endothelial cells, as well as the HIV activity. The claimed compounds may be used for inflammatory diseases and HIV infection treatment.Claims: 15

机译：本发明涉及化学和医学，即涉及式（I）的化合物：或用于治疗炎性疾病和HIV感染的酸加成盐。本发明的概述在于苯并噻吩，苯并呋喃的合成式（1）的吲哚ethiazepineones，恶唑烷酮和diazepinones用作药物组合物中的活性成分，可抑制白细胞对内皮细胞的粘附以及HIV活性。要求保护的化合物可用于炎性疾病和HIV感染治疗。索赔：15

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公开/公告号MD1688F2

专利类型
公开/公告日2001-06-30

原文格式PDF
申请/专利权人 WARNER-LAMBERT COMPANY;
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申请/专利号MD19960000230
发明设计人 BOSCHELLI DIANE HARRIS;CONNOR DAVID THOMAS;KRAMER JAMES BERNARD;UNANGST PAUL CHARLES;
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申请日1995-01-30
分类号C07D495/04;C07D498/04;C07D513/04;A61K31/5517;A61K31/5513;A61P29/02;
国家 MD
入库时间 2022-08-22 01:24:45

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