首页> 外国专利> Methods to detect the presence of blood in a biological sample for detection of lower gastrointestinal bleeding, for the detection of bleeding in the upper GI tract.To diagnose conditions of the disease and to detect the presence of an analyte in a biological sample.

Methods to detect the presence of blood in a biological sample for detection of lower gastrointestinal bleeding, for the detection of bleeding in the upper GI tract.To diagnose conditions of the disease and to detect the presence of an analyte in a biological sample.

机译:检测生物学样品中血液的存在的方法,以检测下消化道出血,胃肠道上段的出血。诊断疾病状况并检测生物学样品中分析物的存在。

摘要

Methods to detect the presence of blood in a biological sample for detection of lower gastrointestinal bleeding, for the detection of bleeding in the upper GI tract.To diagnose conditions of the disease and to detect the presence of an analyte in a biological sample "this invention relates generally to the method for detecting an analyte in aIt shows organic.The first method for detection of blood in the biological sample involves applying the sample to the first region of the test matrix.Detecting globin or haemoglobin by means of immunological evidence in the second region of the test matrix and detect hemo through evidence based on chromogen in the third region of the test matrix.This method is capable of differentiating between the bleeding of the gastrointestinal tract, upper and lower, and it is useful for the diagnosis of diseases of the gastrointestinal tract, in particular,Diseases of the gastrointestinal tract below as the cancer coloretal.The second method disclosed involves the application of the sample, the first region of the test matrix.The sample is left to flow to the second region where she comes in contact with the molecule imunointerativa anti analyte and the conjugate labeled imunointerativo anti analyte.Any complex analyte anti analyte is formed is fixed and detected in the second region.Any imunointerativo labeled anti analyte conjugate non complexed is left flow to the third region where it is detected.
机译:检测生物样品中血液的存在的方法,以检测下消化道出血,并检测上消化道出血。诊断疾病状况并检测生物样品中分析物的存在本发明一般涉及一种检测有机物中被分析物的方法。检测生物样品中血液的第一种方法是将样品施加到测试基质的第一区域。通过免疫学证据检测血红蛋白或血红蛋白。通过在测试矩阵的第三区域中基于色原的证据来检测血液,该方法能够区分胃肠道的出血,上下出血,对疾病的诊断非常有用胃肠道疾病,特别是下面的胃肠道疾病,是癌症的结肠直肠。公开的第二种方法涉及样品的应用,即测试基质的第一个区域。样品流到第二个区域,在该区域中她与分子免疫间隔物抗分析物和缀合物标记的免疫间隔物抗分析物接触。形成的固定物在第二区域中被检测到。任何未复合的免疫interativo标记的抗分析物偶联物都将流向第三区域,在此处进行检测。

著录项

  • 公开/公告号BR9915384A

    专利类型

  • 公开/公告日2001-07-31

    原文格式PDF

  • 申请/专利权人 ENTERIX INC.;

    申请/专利号BR19999915384

  • 发明设计人 HOWARD MILNE CHANDLER;MARC SINATRA;

    申请日1999-11-17

  • 分类号G01N33/72;G01N33/53;C12Q1/28;

  • 国家 BR

  • 入库时间 2022-08-22 01:25:56

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