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Screening method to identify women who risk of premature labor is increasing

机译:甄别早产风险女性的筛查方法

摘要

The present invention provides an early, biochemical indication of increased risk of impending preterm delivery. The method comprises obtaining a cervicovaginal secretion sample from a pregnant patient after week 12 of gestation and determining the level of a local inflammatory product protein or an extracellular matrix protein in the sample. The presence of an elevated level of the selected protein in the sample indicates an increased risk of delivery. The test is a screening assay that can detect women at risk of imminent delivery, as early as two to three weeks prior to delivery.
机译:本发明提供了即将发生的早产风险增加的早期生化指示。该方法包括在妊娠第12周后从怀孕的患者获得宫颈阴道分泌样品,并确定样品中局部炎症产物蛋白或细胞外基质蛋白的水平。样品中所选蛋白质水平的升高表明分娩的风险增加。该测试是一项筛选试验,可以在分娩前两到三周内检测出即将分娩的妇女。

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