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Protection from loss of sensory hair cells in the inner ear by administration of insulin-like growth factor and platelet derived growth factor
Protection from loss of sensory hair cells in the inner ear by administration of insulin-like growth factor and platelet derived growth factor
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机译:通过给予胰岛素样生长因子和血小板衍生的生长因子防止内耳感觉毛细胞丢失
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摘要
The invention relates to a method for protecting sensory hair cells of the inner ear from damage caused by ototoxic drugs, in particular, aminoglycoside antibiotics, by administering to a vertebrate a growth factor, or mixture thereof. Additionally, the method protects against loss of sensory hair cells as a result of aging. In particular, the growth factor is an insulin-like growth factor or platelet-derived growth factor. The invention also relates to a method for detecting protection against an ototoxic drug on sensory hair cells of an inner ear of a vertebrate by a growth factor or biologically active fragment.
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