首页> 外国专利> Protection from loss of sensory hair cells in the inner ear by administration of insulin-like growth factor and platelet derived growth factor

Protection from loss of sensory hair cells in the inner ear by administration of insulin-like growth factor and platelet derived growth factor

机译:通过给予胰岛素样生长因子和血小板衍生的生长因子防止内耳感觉毛细胞丢失

摘要

The invention relates to a method for protecting sensory hair cells of the inner ear from damage caused by ototoxic drugs, in particular, aminoglycoside antibiotics, by administering to a vertebrate a growth factor, or mixture thereof. Additionally, the method protects against loss of sensory hair cells as a result of aging. In particular, the growth factor is an insulin-like growth factor or platelet-derived growth factor. The invention also relates to a method for detecting protection against an ototoxic drug on sensory hair cells of an inner ear of a vertebrate by a growth factor or biologically active fragment.
机译:本发明涉及一种通过给脊椎动物施用生长因子或其混合物来保护内耳感觉毛细胞免受耳毒性药物特别是氨基糖苷类抗生素引起的损害的方法。另外,该方法防止由于老化而引起的感觉毛细胞的损失。特别地,生长因子是胰岛素样生长因子或血小板衍生的生长因子。本发明还涉及一种通过生长因子或生物活性片段检测对脊椎动物内耳感觉毛细胞的耳毒性药物的保护的方法。

著录项

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号