首页> 外国专利> Separation of viral particles, useful e.g. for purification, titration or serotype identification, by chromatography on support having ion-exchange groups attached via flexible linker

Separation of viral particles, useful e.g. for purification, titration or serotype identification, by chromatography on support having ion-exchange groups attached via flexible linker

机译:分离病毒颗粒,例如用于纯化,滴定或血清型鉴定,方法是在色谱柱上通过挠性接头连接有离子交换基团的载体进行色谱分析

摘要

Separation of viral particles (VP) from a biological medium, comprising at least one chromatography step on a matrix support comprising ion-exchange groups, grafted on to the matrix via flexible arms, is new. An Independent claim is also included for a method for quantifying adenovirus by separation on type Q Sepharose XL (RTM) then measuring the absorbance of the chromatography fractions.
机译:从生物介质中分离病毒颗粒(VP)是一项新的工作,该步骤包括在包含离子交换基团的基质支持物上通过柔性臂接枝到基质上的至少一个色谱步骤,该基质支持物具有离子交换基团。还包括通过在Q型琼脂糖XL(RTM)上分离然后测量色谱级分的吸光度来定量腺病毒的方法的独立权利要求。

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