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CAPSULES FOR ORAL PREPARATIONS AND CAPSULE PREPARATIONS FOR ORAL ADMINISTRATION
CAPSULES FOR ORAL PREPARATIONS AND CAPSULE PREPARATIONS FOR ORAL ADMINISTRATION
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机译:口服制剂的胶囊和口服给药的制剂
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摘要
PURPOSE: Capsules for oral preparations are provided which are useful for colon diseases such as colon cancer, ulcerative colon inflammation, constipation and diarrhea, and systemic diseases such as osteoporosis. CONSTITUTION: The capsules for oral preparations undergo no changes in the stomach and small intestine but, after getting to the large intestine, disintegrate and quickly liberate the drugs encapsulated therein at the same time. These capsules have the base which is made from hydroxypropylmethylcellulose (HPMC)optionally containing polyethylene glycol, gelatin or catching. On the surface of the capsule base in which a powder or liquid containing physiological active substance(s) is encapsulated, there is formed a double-coating structure consisting of the inner layer made from a cationic copolymer and the outer layer made from an anionic copolymer.
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