PURPOSE: the cosmetic can be used as cyclooxygenase-2 obstruction and anti-inflammatory agent curing medicine and is provided by improving the cyclooxygenase-2 of blocking effect. CONSTITUTION: separation germinal cell mouse and LPS caused by psoralea corylifolia movement obstruction handles macrophage cyclooxygenase-2 movement are extracted. The material is used as curing medicine and treats a variety of diseases, such as arthritis, and endotoxemia etc. is had something to do, cyclooxygenase-2 and using extracting psoralea corylifolia. Psoralea corylifolia extraction is the anhydrous or hydrate alcohol for being 1-4 with carbon number, ethyl acetate or ether or is added to cosmetic ethyl acetate or butanol or ether, and extraction is segmented in water or ethyl alcohol or methanol enters aqueous methanol extract.
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