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Antiinflammatory and analgesic transdermal gel containing Ketoprofen

机译:含酮洛芬的消炎镇痛透皮凝胶

摘要

Transdermal gels comprising (1) a nonsteroidal antiinflammatory drug of propionic acid derivatives as an effective components (2) poloxamer (3) one or more agent selected from a lower alcohol, propylene glycol, polyethylene glycol and glycerin (4) one or more agent selected from fatty acids, fatty alcohols and methol (5) water or a buffer solution. The gels form thin and pliable films, which are easily washable with water. They possess prolonged antiinflammatory and analgesic activities and excellent physicochemical stability with less systemic side effects and gastric irritation.
机译:包含(1)丙酸衍生物的非甾体类抗炎药作为有效成分的透皮凝胶(2)泊洛沙姆(3)一种或多种选自低级醇,丙二醇,聚乙二醇和甘油的试剂(4)一种或多种选自以下的试剂由脂肪酸,脂肪醇和甲醇(5)制成的水或缓冲溶液。凝胶形成薄而柔韧的薄膜,很容易用水清洗。它们具有延长的抗炎和镇痛作用,以及优异的理化稳定性,具有较少的全身性副作用和对胃的刺激性。

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