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Assessing immunological state of transplant recipients

机译:评估移植受体的免疫状态

摘要

Disclosed herein are methods for monitoring the immunological status of transplant recipients. Fibroblast cells derived from transplanted organs are used in proliferation assays with lymphocytes taken from the recipient after transplantation. The comparison of assay results in the presence of, and in the absence of (or in the presence of reduced levels of) a cytokine growth factor such as interleukin-2, is used to determine whether the organ is being rejected. Also disclosed are kits for practicing these methods.
机译:本文公开了用于监测移植受体的免疫状态的方法。源自移植器官的成纤维细胞与来自受体的淋巴细胞在移植后一起用于增殖测定。在存在和不存在(或存在降低水平的)细胞因子生长因子(例如白介素-2)的情况下进行测定的比较用于确定器官是否被排斥。还公开了用于实践这些方法的试剂盒。

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