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Preparation method of 4 - (1 - hydroxy - (1-methylethyl) furan-2 sulfonamide by reaction with a Grignard Reagent and an ester Group is transformed into Alcohol in an Inert SolventThe reaction Intermediates, The Compound is useful in the synthesis of Derivatives of sulfonylurea inhibitors of interleukin 1.
Preparation method of 4 - (1 - hydroxy - (1-methylethyl) furan-2 sulfonamide by reaction with a Grignard Reagent and an ester Group is transformed into Alcohol in an Inert SolventThe reaction Intermediates, The Compound is useful in the synthesis of Derivatives of sulfonylurea inhibitors of interleukin 1.
Method for preparing Furan sulfonamide compounds of Formula 1 comprising reacting a compound of formual IIWith a reacctivo Grignard reaction in an Inert Solvent to, where r is alkyl (C1 - C6).The Invention also includes compuestosintermediarios formula in which R is alkyl (C1 - C6) and q is Halo, Hydroxy or amino.The Compound of formula I are useful in the synthesis of inhibitors of interleukin 1.
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