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In vitro diagnostic procedure for the determination of dopamine - - hydroxylase activity (specific to the evaluation of the function of the sympathetic nervous system of a patient from a serum sample.And kit for the determination of in vitro activity of dopamine - hydroxylase specific B -
In vitro diagnostic procedure for the determination of dopamine - - hydroxylase activity (specific to the evaluation of the function of the sympathetic nervous system of a patient from a serum sample.And kit for the determination of in vitro activity of dopamine - hydroxylase specific B -
"In vitro diagnostic procedure for the determination of dopamine beta hydroxylase specific activity for the evaluation of function of the sympathetic nervous system of a patient from a sample of SORThe, and kit for the determination of in vitro activity specific for dopamine beta hydroxylase ''.The present invention relates to a process for the determination of in vitro diagnostic activity of dopamine beta hydroxylase specific for evaluation of function of the sympathetic nervous system of a paIn a serum sample, which comprises the steps of: (a) to filter the serum sample to substantially remove drugs and endogenous inhibitors of dopamine beta hydroxylase; (b) incubating the sample filEntry of step (a) with a substrate of dopamine beta hydroxylase for conversion into a detectable compound; (c) determine the quantity of detectable compound to assess the activity of dopamine beta hydroxylASE and compare with a normal sample, by which a quantity smaller than a normal sample is indicative of a function of the sympathetic nervous system is reduced, and a quantity larger than a amostrThe normal is indicative of an increased role of the sympathetic nervous system.A reduction in the function of the sympathetic nervous system is indicative of neurodegenerative diseases, psycho affective and neuroendocrine, cardiovascular, burning, and chronic fatigue.And the effects of stress and panic syndrome. An increase in the function of the sympathetic nervous system is indicative of the effects of stress.
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