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nucleic acid, processes for determining a patient's susceptibility to cancer, for diagnosing cancer in a patient, for predicting the relative prospects for the particular appearance of cancer in a patient, for treating cancer and for determining the loss of heterozygosity in a tissue sample , system to detect the presence or absence of, or mutation, in the region of human chromosome 10, polypeptide, molecule and use of nucleic acid and a molecule.
nucleic acid, processes for determining a patient's susceptibility to cancer, for diagnosing cancer in a patient, for predicting the relative prospects for the particular appearance of cancer in a patient, for treating cancer and for determining the loss of heterozygosity in a tissue sample , system to detect the presence or absence of, or mutation, in the region of human chromosome 10, polypeptide, molecule and use of nucleic acid and a molecule.
"NUCLEIC ACID, PROCESSES TO DETERMINE THE SUSCETIBLITY OF A PATIENT TO CANCER, TO DIAGNOSE CANCER IN A PATIENT, TO PREVENT PERSPECTIVES RELATING TO THE PRIVATE SURGERY OF A CANCER IN A PATIENT, TO TREAT CANCER AND DETERMINATE DETERMINING DETERMINING DETERMINATION TISSUE, SYSTEM FOR DETECTING THE PRESENCE OR ABSENCE OF, OR MUTATION, IN THE HUMAN CHROMOSOME 10, POLYPEPTIDE, MOLECULE AND NUCLEIC ACID AND MOLECULE REGION ". A process for determining a patient's susceptibility to cancer comprising the steps of (i) obtaining a sample containing nucleic acid derived from the patient, and (ii) contacting said nucleic acid with a nucleic acid capable of selectively hybridizing to the chromosome 10 region human, whose region is linked by DNA defined by the D10S541 and D10S215 markers. A nucleic acid capable of selectively hybridizing to the human chromosome 10 region whose region is linked by DNA defined by the D10S541 and D10S215 markers, provided that the nucleic acid is not any of some of the YACs, BACs, PACs or ESTs, defined here. Preferably, said nucleic acid is a prostate tumor suppressor gene.
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