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Procedures for monitoring the concentration of an analyzed and enhance the index of flow patch of a permeante active in a selected area on the body of an individual.To apply a tattoo to a selected area of the skin and to reduce a time lag in the diffusion of an analyzed the blood of an individual and the evaporation of the interstitial fluid and its preVapour pressure
Procedures for monitoring the concentration of an analyzed and enhance the index of flow patch of a permeante active in a selected area on the body of an individual.To apply a tattoo to a selected area of the skin and to reduce a time lag in the diffusion of an analyzed the blood of an individual and the evaporation of the interstitial fluid and its preVapour pressure
"Processes to monitor the concentration of an analyzed and enhance the rate of flow of a patch permeante active in a selected area in the body of a indu00ecvu00ecduo,To apply a tattoo to a selected area of the skin and to reduce a time lag in the diffusion of an examined from the blood of a indivu00ecduo and evaporation of the fluid and its vapor pressure".A process for improving the permeability of the skin (120, 274) to an analysis for diagnostic purposes or to a drug for therapeutic purposes.Is described using the microporau00e7u00e3o and optionally sonic energy and a chemical enhancer.If selected, the sonic energy may be modulated by frequency modulation, amplitude modulation, phase modulation and / or combinations of these.The microporau00e7u00e3o is carried out by (a) removing the corneous (274) by a rapid heating of localized water such that water is vaporized.Thus eroding the cells; (b) puncturing the corneous (274) with a microlanceta calibrated to form a microporo of up to about 1000 a in diameter; (c) removal of the corneous (274).By focusing a beam of sonic energy firmly focused on the corneous (274); (d) a hydraulically puncional the corneous (274) with a jet of fluid from the high pressure.To form a microporo of up to about 1000 a in diameter; or (and) punching the corneous (274) with short pulses of electricity, to form a microporo of up to about 1000 a in diameter.
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