首页> 外国专利> Peptide, composition, vaccine, and, processes to inoculate an animal with the vaccine, affect one or more reproductive or behavioral characteristics of an animal and immunocompromise a pig.

Peptide, composition, vaccine, and, processes to inoculate an animal with the vaccine, affect one or more reproductive or behavioral characteristics of an animal and immunocompromise a pig.

机译:用疫苗接种动物的肽,组合物,疫苗和方法,会影响动物的一种或多种生殖或行为特征,并免疫损害猪。

摘要

"PEPTIDE, COMPOSITION, VACCINE, AND PROCESSES TO INOCULATE AN ANIMAL WITH THE VACCINE, AFFECT ONE OR MORE REPRODUCTIVE OR BEHAVIORAL CHARACTERISTICS OF AN ANIMAL AND IMMUNOCASTRATE A PIG". The invention relates to a vaccine preparation with a modified LHRH repeated peptide in which the amino acid glycine at position (6) of one or both of the LHRH decapeptides that make up the repeated unit is replaced by a dextrorotatory amino acid that contains a side chain to the which a carrier compound can be coupled. In addition, the repeated LHRH peptide can be placed in a repeated dimeric form that is suitable for the production of a vaccine that is effective against LHRH (Luteinizing Hormone Releasing Hormone), also referred to as GnRH (Gonadotropin Releasing Hormone , gonadotropin releasing factor), for immune castration, to inhibit or affect reproductive functions or to affect the behavior of vertebrates in general and domestic animals and man in particular.
机译:“肽,组合物,疫苗和使动物与疫苗接种的过程,会影响一种或多种动物的繁殖或行为特性,并使其猪体内免疫性下降”。本发明涉及具有修饰的LHRH重复肽的疫苗制剂,其中构成重复单元的一个或两个LHRH十肽的(6)位的氨基酸甘氨酸被含有侧链的右旋氨基酸取代可以与之偶联的载体化合物。另外,可以将重复的LHRH肽以适合于生产对LHRH(促黄体激素释放激素)有效的疫苗的重复二聚体形式放置,也称为GnRH(促性腺激素释放激素,促性腺激素释放因子)用于免疫去势,抑制或影响生殖功能或影响脊椎动物的行为,特别是在一般动物,家畜和人类中。

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