首页> 外国专利> Pharmaceutical composition comprising a thiazole derivative for Prevention and Treatment of diseases caused by the abnormal production of cytokines and / or Accelerating the accession of NEUtrofilos and / or abnormal production of TNF alpha, and use of the preparac paa thiazole derivatives

Pharmaceutical composition comprising a thiazole derivative for Prevention and Treatment of diseases caused by the abnormal production of cytokines and / or Accelerating the accession of NEUtrofilos and / or abnormal production of TNF alpha, and use of the preparac paa thiazole derivatives

机译：包含噻唑衍生物的药物组合物，其用于预防和治疗由细胞因子异常产生和/或加速NEUtrofilos的加入和/或TNFα异常产生引起的疾病，以及制备前paa噻唑衍生物的用途

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摘要

Provides an agent to inhibit the production of cytokines and cell adhesion.Compound comprising at least one selected from the Group Organisation of thiazole derivatives represented by the General formula (i),Where R1 is ungru po can have one or more phenyl groups inferiorcomo alkoxy substituents on the phenyl ring and R2 is a respresentado Group by the General formula (ii),In which groups can be equal odiferentes R3, a carboxyl Group, a gr OUP similar or lower alkoxy, and salts thereof.

机译：提供一种抑制细胞因子产生和细胞粘附的试剂。包含选自通式（i）表示的噻唑衍生物的组组织中的至少一种的化合物，其中R 1为非取代基时，可以具有一个或多个苯基亚基或亚基。在苯基环上，R 2是通式（ii）的代表基，其中基团可以是等价的R 3，羧基，gr OUP相似或低级烷氧基及其盐。

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公开/公告号AR009376A1

专利类型
公开/公告日2000-04-12

原文格式PDF
申请/专利权人 OTSUKA PHARMACEUTICAL CO. LTD;
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申请/专利号AR1997P104495
发明设计人
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申请日1997-09-30
分类号A61K31/425;A61K31/44;A61K31/505;C07D277/22;C07D417/04;
国家 AR
入库时间 2022-08-22 01:57:35

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