(symbols are given in p.1 of the formula). Synthesized compounds show inhibiting activity with respect to receptors for angiotensin-II and can be used for production of drugs. The latter can be used for treatment of patients with memory disorder and cognitive function, anxiety state at depression, senile feeble-mindedness and Alzheimer's disease. EFFECT: improved methods of synthesis, enhanced effectiveness of compounds. 15 cl, 7 tbl, 147 ex"/> N-DERIVATIVES OF QUINOLINE OR THEIR ADDITIVE SALTS WITH INORGANIC OR ORGANIC ACIDS OR WITH INORGANIC AND ORGANIC BASES, METHODS OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION BASED ON THEM
首页> 外国专利> N-DERIVATIVES OF QUINOLINE OR THEIR ADDITIVE SALTS WITH INORGANIC OR ORGANIC ACIDS OR WITH INORGANIC AND ORGANIC BASES, METHODS OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION BASED ON THEM

N-DERIVATIVES OF QUINOLINE OR THEIR ADDITIVE SALTS WITH INORGANIC OR ORGANIC ACIDS OR WITH INORGANIC AND ORGANIC BASES, METHODS OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION BASED ON THEM

机译:喹啉或其与无机或有机酸或与无机和有机碱形成的添加剂盐的N-衍生物,其合成方法和基于它们的药物成分

摘要

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to N-derivatives of quinoline of the formula (I) (symbols are given in p.1 of the formula). Synthesized compounds show inhibiting activity with respect to receptors for angiotensin-II and can be used for production of drugs. The latter can be used for treatment of patients with memory disorder and cognitive function, anxiety state at depression, senile feeble-mindedness and Alzheimer's disease. EFFECT: improved methods of synthesis, enhanced effectiveness of compounds. 15 cl, 7 tbl, 147 ex
机译:领域:有机化学,药学。物质:本发明涉及式(I)的喹啉的N-衍生物。<图像文件=“ 00000002.GIF” he =“ 47” imgContent =“ undefined” imgFormat =“ GIF” wi =“ 55” />(符号为在公式的第1页中给出)。合成的化合物对血管紧张素-II的受体显示抑制活性,可用于生产药物。后者可用于治疗患有记忆障碍和认知功能,抑郁症的焦虑状态,老年虚弱的精神病和阿尔茨海默氏病的患者。效果:改进了合成方法,增强了化合物的有效性。 15厘升,7汤匙,147前

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