首页> 外国专利> RADIOACTIVE CHITOSAN CHELATES, RADIOACTIVE CHITOSAN COAGULATES KIT FOR THE PREPARATION OF RADIOACTIVE CHITOSAN CHELATES, PREPARATION AND USE THEREOF

RADIOACTIVE CHITOSAN CHELATES, RADIOACTIVE CHITOSAN COAGULATES KIT FOR THE PREPARATION OF RADIOACTIVE CHITOSAN CHELATES, PREPARATION AND USE THEREOF

机译:放射性壳聚糖螯合试剂盒,放射性壳聚糖螯合试剂盒,放射性壳聚糖螯合物的制备,使用及用途

摘要

The present invention relates to a radioactive chitosan complex in which a radionuclide is labeled with a natural nontoxic, biocompatible, biodegradable polymer chitosan, a radiochitosan aggregated particle and a kit for preparing a radioactive chitosan complex.;The present invention is a method for producing a radioactive chitosan complex solution by reacting a solution of a radionuclide solution with a chitosan, a method for preparing radioactive chitosan aggregated particles by precipitation by adding alkali to the radioactive chitosan complex solution and lyophilizing chitosan to prepare a radioactive chitosan complex A method of making a kit is provided.;In addition, radioactive chitosan complexes and aggregated particles are used as internal radiation therapy for treating various cyst cancers or arthritis, such as liver cancer, brain cancer, ovarian cancer, breast cancer, etc. by directly local injection into the lesions and releasing radiation from the lesions.
机译:本发明涉及一种放射性壳聚糖复合物,其中放射性核素被天然无毒的,生物相容性的,可生物降解的聚合物壳聚糖标记,放射性壳聚糖的聚集颗粒和用于制备放射性壳聚糖复合物的试剂盒。通过使放射性核素溶液与壳聚糖反应而得到的放射性壳聚糖络合物溶液,通过向放射性壳聚糖络合物溶液中添加碱,并冻干壳聚糖以制备放射性壳聚糖络合物而通过沉淀来制备放射性壳聚糖聚集颗粒的方法。此外,放射性壳聚糖复合物和聚集颗粒被用作内部放射疗法,通过直接局部注射到病变中来治疗各种囊性癌或关节炎,例如肝癌,脑癌,卵巢癌,乳腺癌等。并释放出病灶的辐射。

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