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Monoclonal antibodies recognizing human bone marrow stromal cells that regulate the proliferation and differentiation of B cells and fusion cell lines that produce them
Monoclonal antibodies recognizing human bone marrow stromal cells that regulate the proliferation and differentiation of B cells and fusion cell lines that produce them
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机译:识别调节B细胞和产生它们的融合细胞系增殖和分化的人骨髓基质细胞的单克隆抗体
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摘要
The present invention relates to a monoclonal antibody recognizing bone marrow stromal cells and a fusion cell line producing the monoclonal antibody. Specifically, the present invention relates to a fusion cell line prepared by immunizing a bone marrow stromal cell that regulates the proliferation and differentiation of B cells from a patient with multiple myeloma and a monoclonal antibody recognizing the bone marrow stromal cell produced therefrom The monoclonal antibody can be used for the treatment of multiple myeloma induced by tumorigenesis or the like of B cells by regulating the growth and differentiation process of immune cells and developing antibody therapy for controlling the action of bone marrow stromal cells Can be usefully used.
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