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Coup-tfii: an orphan nuclear receptor required for angiogenesis
Coup-tfii: an orphan nuclear receptor required for angiogenesis
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机译:妙招:血管生成所需的孤儿核受体
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摘要
The COUP-TFII gene is essential for angiogenesis. The present invention exploits the role of the COUP-TFII receptor in angiogenesis by the selective use of agonists and antagonists to manipulate angiogenesis. Using agonists of COUP-TFII, angiogenesis can be enhanced, making the agonist a suitable treatment for wounds, promoting recovery from skin-graft surgery and organ transplants. Using COUP-TFII antagonists, angiogenesis can be inhibited, which makes it a suitable treatment for tumor inhibition.
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