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GENETIC POLYMORPHISMS IN THE MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN PROMOTER AND USES THEREOF
GENETIC POLYMORPHISMS IN THE MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN PROMOTER AND USES THEREOF
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机译:微生物甘油三酯转移蛋白启动子中的遗传多态性及其用途
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摘要
The present invention provides diagnostic methods and compositions fordetermining a patient's predisposition towards developing cardiovasculardiseases, which comprises identifying the allelic pattern of genes encodingmicrosomal triglyceride transfer protein (MTP) and comparing the MTP alleicpattern of said patient with the corresponding allelic patterns of humans withno clinical indicators of cardiovascular disease. The invention also providesisolated nucleic acids encoding MTP promoter varients, including probes andmethods for using the isolated nucleic acids for detecting these polymorphismsin individuals.
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