首页> 外国专利> Processes for identifying sex-specific and non-specific molecules to take a sex-specific molecule to differentiate between males and females to separate certain male or female sperm from native semen and to prepare an enriched preparation for non-female and male specific molecules antibody against an epitope of a sex-specific molecule sex-specific molecule isolated and purified contraceptive kit and use of a non-sex specific molecule.

Processes for identifying sex-specific and non-specific molecules to take a sex-specific molecule to differentiate between males and females to separate certain male or female sperm from native semen and to prepare an enriched preparation for non-female and male specific molecules antibody against an epitope of a sex-specific molecule sex-specific molecule isolated and purified contraceptive kit and use of a non-sex specific molecule.

机译:鉴定性别特异性和非特异性分子的方法,以使性别特异性分子在雄性和雌性之间进行区分,以将某些男性或女性精子与天然精液分离,并为非雌性和雄性特异性分子抗体制备丰富的制剂性别特异性分子的表位性别特异性分子分离纯化的避孕药盒以及非性别特异性分子的使用。

摘要

A method for identifying non-sex specific and sex specific molecules associated with animal cell membranes is described. The method involves preparing a cell membrane fraction from adult, fetal, or embryonic animal cells; treating the cell membrane fraction with one or more substances which bind to non-sex specific molecules in the cell membrane fraction to form conjugates between the non-sex specific molecules and the substances; separating the material in the cell membrane fraction which does not bind to the substances to obtain a subfraction containing sex specific molecules; optionally, removing the substances in the conjugates to obtain a subfraction containing non-sex specific molecules; and, isolating the sex specific molecules and optionally non-sex specific molecules in the subfractions. Sex specific and non-sex specific molecules and methods of using the sex specific and non-sex specific molecules for sexing are also described.
机译:描述了一种鉴定与动物细胞膜相关的非性别特异性和性别特异性分子的方法。该方法涉及从成年,胎儿或胚胎动物细胞制备细胞膜级分;用一种或多种与细胞膜级分中的非性别特异性分子结合的物质处理细胞膜级分,以在非性别特异性分子与该物质之间形成结合物;分离不与该物质结合的细胞膜级分中的物质,以获得含有性别特异性分子的亚级分;任选地,去除缀合物中的物质以获得包含非性别特异性分子的亚级分;分离亚组分中的性别特异性分子和任选的非性别特异性分子。还描述了性别特异性和非性别特异性分子,以及使用性别特异性和非性别特异性分子进行性交的方法。

著录项

  • 公开/公告号BR9610235A

    专利类型

  • 公开/公告日1999-07-27

    原文格式PDF

  • 申请/专利权人 UNIVERSITY OF GUELPH;

    申请/专利号BR19969610235

  • 发明设计人 STAN R. BLECHER;

    申请日1996-08-09

  • 分类号G01N33/569;G01N33/68;A61K35/52;C07K14/705;C07K16/28;A61K39/395;

  • 国家 BR

  • 入库时间 2022-08-22 02:28:15

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