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Regenerative manner null of producing and skeletal system the glenoid cartilage and constituent and skeletal system transplantation system for bone regeneration
Regenerative manner null of producing and skeletal system the glenoid cartilage and constituent and skeletal system transplantation system for bone regeneration
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机译:产生和骨骼系统的再生方式关节盂软骨及其成分和骨骼系统移植系统的骨再生
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摘要
A composition for the regeneration of articular cartilage and bones by implantation comprising cells expressing a chondrocyte phenotype (80 x 106 cells/ml), namely bone marrow derived chondrocytes or osteoblasts of autologous or homologous origin, or homologous committed chondrocytes, or autologous or homologous muscle fibroblast derived chondrocytes or any other progenital cells from mesenchymal origin, which are embedded in a biodegradable, biocompatible, biological resorbable immobilization vehicle (BRIV) adhesive glue consisting of fibrinogen, thrombin, CaCl2, protease inhibitor, and at least 10%, preferably 15-30%, serum, and a process for the preparation of such composition as skeletal tissue implant. A portion of the implant may comprise a bone segment or a bone substitute.
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