首页> 外国专利> POLY-(α-L-ASPARTIC ACID), POLY-(α-L-GLUTAMIC ACID) AND COPOLYMERS OF L-ASP AND L-GLU, METHOD FOR THEIR PRODUCTION AND THEIR USE

POLY-(α-L-ASPARTIC ACID), POLY-(α-L-GLUTAMIC ACID) AND COPOLYMERS OF L-ASP AND L-GLU, METHOD FOR THEIR PRODUCTION AND THEIR USE

机译:L-ASP和L-GLU的聚(α-L-ASP酸),聚(α-L-谷氨酸)和共聚物,其生产方法和用途

摘要

The invention provides Poly-(α-L-aspartic acid) (= poly-L-α-Asp), Poly-(α-L-glutamic acid) and new copolymers of L-Asp and L-Glu with essentially α-linkages as well as salts of said polymers and copolymers. A method for producing said polyamino acids comprises employing an oligonucleotide construct encoding the sequence of the desired polymer, cloning the oligonucleotide into a plasmid, transformation of host cells with the plasmid and expression of the genetic information. Because of their good biological degradability the new poly-L-α-amino acids can be used as co-builders, sequestering agents and corrosion inhibitors.
机译:本发明提供了聚-(α-L-天冬氨酸)(=聚-L-α-Asp),聚(α-L-谷氨酸)以及具有基本α-键的L-Asp和L-Glu的新共聚物。以及所述聚合物和共聚物的盐。生产所述聚氨基酸的方法包括使用编码所需聚合物序列的寡核苷酸构建体,将寡核苷酸克隆到质粒中,用该质粒转化宿主细胞并表达遗传信息。由于其良好的生物降解性,新的聚-L-α-氨基酸可用作助助剂,螯合剂和腐蚀抑制剂。

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