首页> 外国专利> CRYSTALLINE FORMS OF MONOHYDRATES OF ENDO-2,3-DIHYDRO-N-(8-METHYL-8-AZABICYCLO 3.2.1 OCT-3-YLO)-2-OXO-1H-BENZIMIDAZOLO-1-CARBOXYLAMIDE, AND ENDO-3-ETHYL-2,3-DIHYDRO-N-(8-METHYL-8-AZABICYCLO 3.2.1 OCT-3-YLO)-2-OXO-1H-BENZIMIDAZOLO-1-CARBOXYLAMIDE HYDROCHLORIDES, METHODS OF OBTAINING SAMES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

CRYSTALLINE FORMS OF MONOHYDRATES OF ENDO-2,3-DIHYDRO-N-(8-METHYL-8-AZABICYCLO 3.2.1 OCT-3-YLO)-2-OXO-1H-BENZIMIDAZOLO-1-CARBOXYLAMIDE, AND ENDO-3-ETHYL-2,3-DIHYDRO-N-(8-METHYL-8-AZABICYCLO 3.2.1 OCT-3-YLO)-2-OXO-1H-BENZIMIDAZOLO-1-CARBOXYLAMIDE HYDROCHLORIDES, METHODS OF OBTAINING SAMES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

机译：ENDO-2,3-二氢-N-（8-甲基-8-氮杂双环[3.2.1] OCT-3-YLO）-2-OXO-1H-苯并咪唑基-1-羧酰胺的单羟基结晶形式3-乙基-2,3-二氢-N-（8-甲基-8-氮杂双环[3.2.1] OCT-3-YLO）-2-OXO-1H-苯并咪唑基-1-羧酰胺氢吡咯，获得盐的方法和包含它们的药物成分

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Crystalline monohydrates of endo-2,3-dihydro-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-2-oxo-1H-ben zimidazole-1-carboxamide hydrochloride and of endo-3-ethyl-2,3-dihydro-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-2-ox o-1H-benzimidazole-1-carboxamide hydrochloride of formula CHEM (Compound 2a: R = H (Compound 2b: R = C2H5 the processes for their preparation and pharmaceutical compositions containing them. IMAGE

机译：-2,3-二氢-N-（8-甲基-8-氮杂双环[3.2.1]辛-3-基）-2-氧代-1H-苯甲杂咪唑-1-羧酰胺盐酸盐的结晶一水合物和式的3-乙基-2,3-二氢-N-（8-甲基-8-氮杂双环[3.2.1]辛-3-基）-2-氧邻-1H-苯并咪唑-1-羧酰胺盐酸盐（化合物2a：R = H>（化合物2b：R = C2H5>制备方法和含有它们的药物组合物。<图像>

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公开/公告号PL172890B1

专利类型
公开/公告日1997-12-31

原文格式PDF
申请/专利权人 BOEHRINGER INGELHEIM ITALIA SPA;
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申请/专利号PL19930298263
发明设计人 CEREDA ENZO;EZHAYA ANTOINE;TURCONI MARCO;DUBINI ENRICA;MAFFIONE GRAZIA;
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申请日1993-03-25
分类号C07D403/12;A61K31/40;
国家 PL
入库时间 2022-08-22 02:56:46

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