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stimulation of the post extrasystolischen potentiation with a feedback from a physiological meszsonde

机译:生理性中速回声的反馈刺激收缩期后增强

摘要

A post-extrasystolic potentiation (PESP) cardiac pacing energy stimulator for applying paired and/or triggered pacing stimulation pulses to the right atrium and/or ventricle incorporating one or more sensors, such as a venous oxygen saturation, ventricular, atrial, or arterial blood pressure, or intracardiac or systemic blood flow sensor, and signal processing circuitry for controlling the frequency of or number of heart cycles between periodic delivery of triggered or paired pacing to induce PESP for the treatment of congestive heart failure or other cardiac dysfunctions. Preferably, a first sensor, e.g., a ventricular or arterial blood pressure or flow sensor, is employed to monitor the performance of the heart, and develop a cardiac performance index (CPI) and a second sensor, e.g., an oxygen saturation sensor positioned in the coronary sinus, is employed to monitor cardiac muscle stress and develop a cardiac stress index (CSI) to balance performance and stress. The PESP stimulator may be incorporated into a dual chamber (DDD) pacing system with or without physiologic rate control and with or without backup cardioversion/defibrillation therapy capabilities or in a separate, single purpose device. The PESP stimulator has particular application in atrial stimulation for augmenting filling of the ventricles.
机译:心脏收缩后增强(PESP)心脏起搏能量刺激器,用于将配对和/或触发的起搏刺激脉冲施加到右心房和/或心室,并结合一个或多个传感器,例如静脉血氧饱和度,心室,心房或动脉血压力,心脏内或全身血流传感器以及信号处理电路,用于控制周期性或周期性起搏或配对起搏之间的心动周期频率或次数,以诱导PESP来治疗充血性心力衰竭或其他心脏功能障碍。优选地,采用第一传感器,例如心室或动脉血压或流量传感器来监测心脏的性能,并产生心脏性能指数(CPI),并采用第二传感器,例如定位在心脏中的氧饱和度传感器。冠状窦被用于监测心肌压力并发展出心脏压力指数(CSI)以平衡性能和压力。可以将PESP刺激器结合到双腔(DDD)起搏系统中,该系统可以具有或不具有生理速率控制功能,并且可以具有或不具有备用心脏复律/除颤治疗功能,或者可以包含在单独的单一用途设备中。 PESP刺激器在心房刺激中具有特殊应用,可增强心室的充盈。

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