首页> 外国专利> For lys46, asp97, asp113 and lys46, asp113, asp137 thaumatin - i dna coding for polypeptides

For lys46, asp97, asp113 and lys46, asp113, asp137 thaumatin - i dna coding for polypeptides

机译:对于[lys46,asp97,asp113]和[lys46,asp113,asp137]索马甜-编码多肽的dna

摘要

Genes are disclosed which are capable of directing the synthesis in a selected host microorganism of thaumatin I polypeptides having improved taste characteristics characterized by having the amino acid sequence of natural thaumatin I including a lysine amino acid residue substituted for asparagine in the 46th position from the amino terminal end, an aspartate amino acid residue substituted for asparagine in the 113th position from the amino terminal end and an aspartate amino acid residue substituted for lysine at either the 97th or 137th residue from the amino terminal end.
机译:公开了能够指导选择的宿主微生物中合成具有改善的味觉特征的索马甜I多肽的基因,其特征在于天然索马甜I的氨基酸序列在其氨基的第46位具有赖氨酸氨基酸残基取代天冬酰胺在末端,从氨基末端起在第113位的天冬氨酸残基被天冬酰胺取代,在从氨基末端起第97或137位的残基被天冬氨酸残基取代。

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